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September 23, 2025
Ep -
101

Grey's Anatomy stars Jessica Capshaw & Camilla Luddington on Friendship, Motherhood & Mental Health

On this episode of SHE MD, hosts Mary Alice Haney and Dr. Thaïs Aliabadi welcome Grey's Anatomy stars Jessica Capshaw and Camilla Luddington. The actresses discuss their friendship, motherhood, and mental health experiences. They also share insights from their popular podcast "Call It What It Is" and offer advice on relationships and personal growth.

About the Guest

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Jessica Capshaw is best known for her role as “Dr. Arizona Robbins” in the long-running TV series Grey's Anatomy.

Capshaw can most recently be seen opposite Grace Van Patten in the hit Hulu series

“Tell me Lies,” which is based on the best-selling novel by Carola. 

Capshaw earned her Bachelor of Arts degree in English literature at  Brown University. In addition to this, she also attended the Royal Academy of Dramatic Arts during her summer breaks, where she starred as “Puck” in a production of “A Midsummer Night’s Dream.”

Capshaw is based in New York.

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Currently starring on ABC’s hit medical drama series Grey’s Anatomy, Camilla Luddington has the gift of portraying characters with both strength and vulnerability, and her Dr. Jo Wilson displays plenty of both as she finds her way through complicated storylines of love and career.

The sci-fi/fantasy world has come to love her too for her embodiment of Lara Croft, a different kind of heroine, in the video game Tomb Raider. When the game was released in 2013,

critics praised Luddington for giving the classic icon a much-needed reboot. In 2015, Camilla reprised her role as Lara in the video game Rise of the Tomb Raider, and continued her work as this character in the anticipated video game Shadow of the Tomb Raider.

Californication, she portrayed Lizzie, the seemingly sweet English nanny who would do whatever it took to make it in L.A.

Jessica Capshaw & Camilla Luddington’s Key Takeaways:

  • Laugh Together: Make laughter a priority in your relationship to navigate life's challenges.
  • Learn to Fight Fair: Develop healthy arguing skills, avoiding low blows and learning to apologize.
  • Find Your Foundation: Trust in your ability to rebuild and grow, even after significant loss.
  • Embrace Strategy: View being strategic and ambitious as positive traits that can lead to success.
  • Balance Push and Pull: Calibrate when to challenge yourself and when to be gentle for optimal growth.
  • Reframe Obstacles: Approach challenges with a "how can I not?" mindset instead of doubting yourself.
  • Build a Support Network: Seek out individuals who can assist you in areas where you need guidance.

In This Episode: 

(00:00) Introduction

(01:06) Mary Alice introduces Jessica and Camilla

(05:03) Importance of authentic women's friendships

(08:09) Origins and goals of their podcast

(12:07) Discussing pregnancy loss and mental health

(15:34) Camilla's experience with postpartum anxiety

(20:48) Dealing with Tinnitus and Anxiety

(23:52) Balancing motherhood and acting careers

(29:38) Redefining Success

(31:29) Advice for maintaining long-standing marriages

(33:59) Lessons for their younger selves

(35:56) Camilla on rebuilding after losing her mother

(39:50) Closing thoughts on ambition and inspiration

RESOURCES:

CALL IT WHAT IT IS PODCAST INSTAGRAM

CALL IT WHAT IT IS PODCAST TIKTOK